PaHa03g07940

Functional evidence

eggNOG

Preferred name: LOC104589243 | Seed ortholog: 337451.A0A443NBE8 | COG: S | eggNOG OG: Presenilin@131567|A-1, Presenilin@33090|IG-20

Gene Ontology

GO:0000045 autophagosome assembly; GO:0000122 negative regulation of transcription by RNA polymerase II; GO:0001568 blood vessel development; GO:0001666 response to hypoxia; GO:0001708 cell fate specification; GO:0001756 somitogenesis; GO:0001764 neuron migration; GO:0001921 positive regulation of receptor recycling; GO:0001933 negative regulation of protein phosphorylation; GO:0001934 positive regulation of protein phosphorylation; GO:0001942 hair follicle development; GO:0001946 lymphangiogenesis; GO:0001947 heart looping; GO:0001964 startle response; GO:0002038 positive regulation of L-glutamate import across plasma membrane; GO:0002244 hematopoietic progenitor cell differentiation; GO:0002265 astrocyte activation involved in immune response; GO:0002286 T cell activation involved in immune response; GO:0002573 myeloid leukocyte differentiation; GO:0003407 neural retina development; GO:0003674 molecular_function; GO:0004175 endopeptidase activity; GO:0004190 aspartic-type endopeptidase activity; GO:0005262 calcium channel activity; GO:0005515 protein binding; GO:0005798 Golgi-associated vesicle; GO:0006469 negative regulation of protein kinase activity; GO:0006508 proteolysis; GO:0006509 membrane protein ectodomain proteolysis; GO:0006816 calcium ion transport; GO:0006839 mitochondrial transport; GO:0006874 intracellular calcium ion homeostasis; GO:0006909 phagocytosis; GO:0006914 autophagy; GO:0006915 apoptotic process; GO:0006974 DNA damage response; GO:0006979 response to oxidative stress; GO:0007219 Notch signaling pathway; GO:0007220 Notch receptor processing; GO:0007286 spermatid development; GO:0007399 nervous system development; GO:0007420 brain development; GO:0007507 heart development; GO:0007611 learning or memory; GO:0007613 memory; GO:0008013 beta-catenin binding; GO:0008104 intracellular protein localization; GO:0008233 peptidase activity; GO:0009101 glycoprotein biosynthetic process; GO:0009791 post-embryonic development; GO:0010467 gene expression; GO:0010468 regulation of gene expression; GO:0010506 regulation of autophagy; GO:0010628 positive regulation of gene expression; GO:0010629 negative regulation of gene expression; GO:0010975 regulation of neuron projection development; GO:0015031 protein transport; GO:0015871 choline transport; GO:0016048 detection of temperature stimulus; GO:0016485 protein processing; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0018991 egg-laying behavior; GO:0019896 axonal transport of mitochondrion; GO:0021549 cerebellum development; GO:0021795 cerebral cortex cell migration; GO:0021870 Cajal-Retzius cell differentiation; GO:0021904 dorsal/ventral neural tube patterning; GO:0021987 cerebral cortex development; GO:0022008 neurogenesis; GO:0022603 regulation of anatomical structure morphogenesis; GO:0030165 PDZ domain binding; GO:0030182 neuron differentiation; GO:0030318 melanocyte differentiation; GO:0030326 embryonic limb morphogenesis; GO:0030587 sorocarp development; GO:0030900 forebrain development; GO:0031149 sorocarp stalk cell differentiation; GO:0031293 membrane protein intracellular domain proteolysis; GO:0031333 negative regulation of protein-containing complex assembly; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0032469 endoplasmic reticulum calcium ion homeostasis; GO:0032760 positive regulation of tumor necrosis factor production; GO:0034205 amyloid-beta formation; GO:0035282 segmentation; GO:0035333 Notch receptor processing, ligand-dependent; GO:0035556 intracellular signal transduction; GO:0036269 swimming behavior; GO:0040011 locomotion; GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway; GO:0042307 positive regulation of protein import into nucleus; GO:0042462 eye photoreceptor cell development; GO:0042500 aspartic endopeptidase activity, intramembrane cleaving; GO:0042982 amyloid precursor protein metabolic process; GO:0042987 amyloid precursor protein catabolic process; GO:0043011 myeloid dendritic cell differentiation; GO:0043065 positive regulation of apoptotic process; GO:0043066 negative regulation of apoptotic process; GO:0043406 positive regulation of MAP kinase activity; GO:0043524 negative regulation of neuron apoptotic process; GO:0043589 skin morphogenesis; GO:0044351 macropinocytosis; GO:0044671 sorocarp spore cell differentiation; GO:0045176 apical protein localization; GO:0045296 cadherin binding; GO:0045747 positive regulation of Notch signaling pathway; GO:0045821 positive regulation of glycolytic process; GO:0045860 positive regulation of protein kinase activity; GO:0045893 positive regulation of DNA-templated transcription; GO:0048143 astrocyte activation; GO:0048167 regulation of synaptic plasticity; GO:0048286 lung alveolus development; GO:0048489 synaptic vesicle transport; GO:0048515 spermatid differentiation; GO:0048538 thymus development; GO:0048666 neuron development; GO:0048705 skeletal system morphogenesis; GO:0048854 brain morphogenesis; GO:0048858 cell projection morphogenesis; GO:0050435 amyloid-beta metabolic process; GO:0050673 epithelial cell proliferation; GO:0050771 negative regulation of axonogenesis; GO:0050808 synapse organization; GO:0050820 positive regulation of coagulation; GO:0050852 T cell receptor signaling pathway; GO:0051117 ATPase binding; GO:0051402 neuron apoptotic process; GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis; GO:0051604 protein maturation; GO:0051966 regulation of synaptic transmission, glutamatergic; GO:0052548 regulation of endopeptidase activity; GO:0055074 calcium ion homeostasis; GO:0060048 cardiac muscle contraction; GO:0060070 canonical Wnt signaling pathway; GO:0060075 regulation of resting membrane potential; GO:0060090 molecular adaptor activity; GO:0060291 long-term synaptic potentiation; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0060999 positive regulation of dendritic spine development; GO:0061024 membrane organization; GO:0061053 somite development; GO:0070050 neuron cellular homeostasis; GO:0070851 growth factor receptor binding; GO:0071632 optomotor response; GO:0098609 cell-cell adhesion; GO:0098693 regulation of synaptic vesicle cycle; GO:0098712 L-glutamate import across plasma membrane; GO:0099175 regulation of postsynapse organization; GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway; GO:0110011 regulation of basement membrane organization; GO:0110097 regulation of calcium import into the mitochondrion; GO:0140249 protein catabolic process at postsynapse; GO:0150076 neuroinflammatory response; GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:1904646 cellular response to amyloid-beta; GO:1905908 positive regulation of amyloid fibril formation; GO:1905938 positive regulation of germ cell proliferation; GO:1990535 neuron projection maintenance; GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process; GO:2001234 negative regulation of apoptotic signaling pathway

KEGG

KO: K04505 | Pathway: 04310, 04330, 04361, 04722, 05010, 05022, 05165 | BRITE: 00001, 01002