Chr03.g27632

Functional evidence

eggNOG

218851.Aquca_007_00484.1,I,[Catalyzes the third of the four reactions of the long- chain fatty acids elongation cycle. This endoplasmic reticulum- bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators]

Gene Ontology

Catalyzes the third of the four reactions of the long- chain fatty acids elongation cycle. This endoplasmic reticulum- bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators | GO:0006082//organic acid metabolic process; GO:0006629//lipid metabolic process; GO:0006631//fatty acid metabolic process; GO:0006633//fatty acid biosynthetic process; GO:0006643//membrane lipid metabolic process; GO:0006665//sphingolipid metabolic process; GO:0006807//nitrogen compound metabolic process; GO:0008150//biological_process; GO:0008152//metabolic process; GO:0008610//lipid biosynthetic process; GO:0009058//biosynthetic process; GO:0009987//cellular process; GO:0016053//organic acid biosynthetic process; GO:0019752//carboxylic acid metabolic process; GO:0030148//sphingolipid biosynthetic process; GO:0030497//fatty acid elongation; GO:0032787//monocarboxylic acid metabolic process; GO:0043436//oxoacid metabolic process; GO:0044237//cellular metabolic process; GO:0044238//primary metabolic process; GO:0044249//cellular biosynthetic process; GO:0044255//cellular lipid metabolic process; GO:0044281//small molecule metabolic process; GO:0044283//small molecule biosynthetic process; GO:0046394//carboxylic acid biosynthetic process; GO:0046467//membrane lipid biosynthetic process; GO:0071704//organic substance metabolic process; GO:0072330//monocarboxylic acid biosynthetic process; GO:1901564//organonitrogen compound metabolic process; GO:1901566//organonitrogen compound biosynthetic process; GO:1901576//organic substance biosynthetic process | GO:0005575//cellular_component; GO:0005622//intracellular; GO:0005623//cell; GO:0005737//cytoplasm; GO:0005783//endoplasmic reticulum; GO:0005789//endoplasmic reticulum membrane; GO:0012505//endomembrane system; GO:0016020//membrane; GO:0016021//integral component of membrane; GO:0030176//integral component of endoplasmic reticulum membrane; GO:0031224//intrinsic component of membrane; GO:0031227//intrinsic component of endoplasmic reticulum membrane; GO:0031984//organelle subcompartment; GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network; GO:0043226//organelle; GO:0043227//membrane-bounded organelle; GO:0043229//intracellular organelle; GO:0043231//intracellular membrane-bounded organelle; GO:0044422//organelle part; GO:0044424//intracellular part; GO:0044425//membrane part; GO:0044432//endoplasmic reticulum part; GO:0044444//cytoplasmic part; GO:0044446//intracellular organelle part; GO:0044464//cell part; GO:0098827//endoplasmic reticulum subcompartment | GO:0003674//molecular_function; GO:0003824//catalytic activity; GO:0016829//lyase activity; GO:0016835//carbon-oxygen lyase activity; GO:0016836//hydro-lyase activity; GO:0018812//3-hydroxyacyl-CoA dehydratase activity

KEGG

K10703 | HACD, PHS1, PAS2

NR

RWR77313.1 very-long-chain 3R-3-hydroxyacyl-CoA dehydratase PASTICCINO 2A [Cinnamomum micranthum f. kanehirae]

Swiss-Prot

Q7XSZ4.2 RecName: Full=Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2A; AltName: Full=3-hydroxyacyl-CoA dehydratase PASTICCINO 2A; Short=HACD; Short=PAS2A; AltName: Full=Protein tyrosine phosphatase-like protein [Oryza sativa Japonica Group]