Pa11g1535

Functional evidence

eggNOG

Preferred name: FBW2 | Seed ortholog: 337451.A0A3S3PKD7 | COG: S | eggNOG OG: F-box-like@131567|Asa-23, F-box-like@1437183|fqe-55, F-box-like@2759|BKN-24, F-box-like@58023|baG-49, LRR_6@131567|Uj-15, LRR_6@1437183|ItO-33, LRR_6@3398|CWh-25

Gene Ontology

GO:0000122 negative regulation of transcription by RNA polymerase II; GO:0000781 chromosome, telomeric region; GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding; GO:0001659 temperature homeostasis; GO:0002221 pattern recognition receptor signaling pathway; GO:0002227 innate immune response in mucosa; GO:0002253 activation of immune response; GO:0002606 positive regulation of dendritic cell antigen processing and presentation; GO:0002710 negative regulation of T cell mediated immunity; GO:0002720 positive regulation of cytokine production involved in immune response; GO:0002732 positive regulation of dendritic cell cytokine production; GO:0002830 positive regulation of type 2 immune response; GO:0002862 negative regulation of inflammatory response to antigenic stimulus; GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin; GO:0003674 molecular_function; GO:0003713 transcription coactivator activity; GO:0003714 transcription corepressor activity; GO:0003779 actin binding; GO:0005515 protein binding; GO:0005575 cellular_component; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0005737 cytoplasm; GO:0005739 mitochondrion; GO:0005741 mitochondrial outer membrane; GO:0005794 Golgi apparatus; GO:0005813 centrosome; GO:0005829 cytosol; GO:0005856 cytoskeleton; GO:0005886 plasma membrane; GO:0005938 cell cortex; GO:0006355 regulation of DNA-templated transcription; GO:0006952 defense response; GO:0006954 inflammatory response; GO:0006963 positive regulation of antibacterial peptide biosynthetic process; GO:0006965 positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria; GO:0007165 signal transduction; GO:0007249 canonical NF-kappaB signal transduction; GO:0007283 spermatogenesis; GO:0008150 biological_process; GO:0008284 positive regulation of cell population proliferation; GO:0009595 detection of biotic stimulus; GO:0009617 response to bacterium; GO:0009986 cell surface; GO:0010508 positive regulation of autophagy; GO:0016045 detection of bacterium; GO:0016323 basolateral plasma membrane; GO:0016324 apical plasma membrane; GO:0016605 PML body; GO:0019005 SCF ubiquitin ligase complex; GO:0019828 aspartic-type endopeptidase inhibitor activity; GO:0019897 extrinsic component of plasma membrane; GO:0019899 enzyme binding; GO:0019901 protein kinase binding; GO:0019966 interleukin-1 binding; GO:0030277 maintenance of gastrointestinal epithelium; GO:0030544 Hsp70 protein binding; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0031398 positive regulation of protein ubiquitination; GO:0031982 vesicle; GO:0032090 Pyrin domain binding; GO:0032098 regulation of appetite; GO:0032494 response to peptidoglycan; GO:0032495 response to muramyl dipeptide; GO:0032496 response to lipopolysaccharide; GO:0032498 detection of muramyl dipeptide; GO:0032500 muramyl dipeptide binding; GO:0032688 negative regulation of interferon-beta production; GO:0032689 negative regulation of type II interferon production; GO:0032695 negative regulation of interleukin-12 production; GO:0032701 negative regulation of interleukin-18 production; GO:0032703 negative regulation of interleukin-2 production; GO:0032715 negative regulation of interleukin-6 production; GO:0032720 negative regulation of tumor necrosis factor production; GO:0032731 positive regulation of interleukin-1 beta production; GO:0032733 positive regulation of interleukin-10 production; GO:0032735 positive regulation of interleukin-12 production; GO:0032740 positive regulation of interleukin-17 production; GO:0032741 positive regulation of interleukin-18 production; GO:0032755 positive regulation of interleukin-6 production; GO:0032757 positive regulation of interleukin-8 production; GO:0032760 positive regulation of tumor necrosis factor production; GO:0032874 positive regulation of stress-activated MAPK cascade; GO:0032966 negative regulation of collagen biosynthetic process; GO:0032991 protein-containing complex; GO:0034136 negative regulation of toll-like receptor 2 signaling pathway; GO:0034341 response to type II interferon; GO:0034976 response to endoplasmic reticulum stress; GO:0035187 hatching behavior; GO:0035556 intracellular signal transduction; GO:0036335 intestinal stem cell homeostasis; GO:0038066 p38MAPK cascade; GO:0038187 pattern recognition receptor activity; GO:0039536 negative regulation of RIG-I signaling pathway; GO:0040019 positive regulation of embryonic development; GO:0042742 defense response to bacterium; GO:0042802 identical protein binding; GO:0042803 protein homodimerization activity; GO:0042826 histone deacetylase binding; GO:0042834 peptidoglycan binding; GO:0043065 positive regulation of apoptotic process; GO:0043067 regulation of programmed cell death; GO:0043123 positive regulation of canonical NF-kappaB signal transduction; GO:0043124 negative regulation of canonical NF-kappaB signal transduction; GO:0043130 ubiquitin binding; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043330 response to exogenous dsRNA; GO:0043408 regulation of MAPK cascade; GO:0043410 positive regulation of MAPK cascade; GO:0043531 ADP binding; GO:0043549 regulation of kinase activity; GO:0044546 NLRP3 inflammasome complex assembly; GO:0044877 protein-containing complex binding; GO:0045087 innate immune response; GO:0045089 positive regulation of innate immune response; GO:0045335 phagocytic vesicle; GO:0045345 positive regulation of MHC class I biosynthetic process; GO:0045348 positive regulation of MHC class II biosynthetic process; GO:0045747 positive regulation of Notch signaling pathway; GO:0045824 negative regulation of innate immune response; GO:0045892 negative regulation of DNA-templated transcription; GO:0045944 positive regulation of transcription by RNA polymerase II; GO:0046330 positive regulation of JNK cascade; GO:0046597 host-mediated suppression of symbiont invasion; GO:0046645 positive regulation of gamma-delta T cell activation; GO:0046677 response to antibiotic; GO:0048874 host-mediated modulation of intestinal microbiota composition; GO:0050679 positive regulation of epithelial cell proliferation; GO:0050700 CARD domain binding; GO:0050727 regulation of inflammatory response; GO:0050728 negative regulation of inflammatory response; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0050766 positive regulation of phagocytosis; GO:0050829 defense response to Gram-negative bacterium; GO:0050830 defense response to Gram-positive bacterium; GO:0050871 positive regulation of B cell activation; GO:0051000 positive regulation of nitric-oxide synthase activity; GO:0051293 establishment of spindle localization; GO:0051607 defense response to virus; GO:0051879 Hsp90 protein binding; GO:0060090 molecular adaptor activity; GO:0060333 type II interferon-mediated signaling pathway; GO:0060335 positive regulation of type II interferon-mediated signaling pathway; GO:0060339 negative regulation of type I interferon-mediated signaling pathway; GO:0060340 positive regulation of type I interferon-mediated signaling pathway; GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding; GO:0061702 canonical inflammasome complex; GO:0070269 pyroptotic inflammatory response; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway; GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway; GO:0070534 protein K63-linked ubiquitination; GO:0070936 protein K48-linked ubiquitination; GO:0071222 cellular response to lipopolysaccharide; GO:0071224 cellular response to peptidoglycan; GO:0071225 cellular response to muramyl dipeptide; GO:0071257 cellular response to electrical stimulus; GO:0071346 cellular response to type II interferon; GO:0071360 cellular response to exogenous dsRNA; GO:0071639 positive regulation of monocyte chemotactic protein-1 production; GO:0072559 NLRP3 inflammasome complex; GO:0089720 caspase binding; GO:0090022 regulation of neutrophil chemotaxis; GO:0097039 protein linear polyubiquitination; GO:0106310 protein serine kinase activity; GO:0106333 subcortical maternal complex; GO:0140297 DNA-binding transcription factor binding; GO:0140367 antibacterial innate immune response; GO:0140374 antiviral innate immune response; GO:1900017 positive regulation of cytokine production involved in inflammatory response; GO:1900750 oligopeptide binding; GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction; GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction; GO:1901526 positive regulation of mitophagy; GO:1902523 positive regulation of protein K63-linked ubiquitination; GO:1904417 positive regulation of xenophagy; GO:1905761 SCF ubiquitin ligase complex binding; GO:1990168 protein K33-linked deubiquitination; GO:2000110 negative regulation of macrophage apoptotic process

KEGG

EC: ec:2.7.11.1 | KO: K08060, K08727, K10165, K10273, K10275, K10278, K12653, K17579, K19409, K20864, K22265, K22614, K22615, K22662, K22663, K22665, K22666 | Pathway: 04137, 04612, 04621, 04622, 04668, 05130, 05132, 05133, 05145, 05152, 05164, 05321, 05340 | BRITE: 00001, 01000, 01001, 01009, 04054, 04121, 04131, 04812