Pa05g1921

Functional evidence

eggNOG

Preferred name: ATPEN2 | Seed ortholog: 337451.A0A3S3P4V4 | COG: S | eggNOG OG: PTEN_C2@131567|A-1*, PTEN_C2@2759|If-17

Gene Ontology

GO:0000281 mitotic cytokinesis; GO:0001525 angiogenesis; GO:0001568 blood vessel development; GO:0001649 osteoblast differentiation; GO:0001931 uropod; GO:0002164 larval development; GO:0002275 myeloid cell activation involved in immune response; GO:0002902 regulation of B cell apoptotic process; GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity; GO:0004721 phosphoprotein phosphatase activity; GO:0004722 protein serine/threonine phosphatase activity; GO:0004725 protein tyrosine phosphatase activity; GO:0005161 platelet-derived growth factor receptor binding; GO:0005515 protein binding; GO:0005546 phosphatidylinositol-4,5-bisphosphate binding; GO:0005575 cellular_component; GO:0005576 extracellular region; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0005737 cytoplasm; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0006470 protein dephosphorylation; GO:0006606 protein import into nucleus; GO:0006661 phosphatidylinositol biosynthetic process; GO:0006914 autophagy; GO:0006915 apoptotic process; GO:0006935 chemotaxis; GO:0007010 cytoskeleton organization; GO:0007032 endosome organization; GO:0007056 spindle assembly involved in female meiosis; GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway; GO:0007270 neuron-neuron synaptic transmission; GO:0007416 synapse assembly; GO:0007417 central nervous system development; GO:0007425 epithelial cell fate determination, open tracheal system; GO:0007507 heart development; GO:0007552 metamorphosis; GO:0007584 response to nutrient; GO:0007611 learning or memory; GO:0007613 memory; GO:0007626 locomotory behavior; GO:0007635 chemosensory behavior; GO:0008013 beta-catenin binding; GO:0008138 protein tyrosine/serine/threonine phosphatase activity; GO:0008284 positive regulation of cell population proliferation; GO:0008285 negative regulation of cell population proliferation; GO:0008340 determination of adult lifespan; GO:0008360 regulation of cell shape; GO:0008361 regulation of cell size; GO:0009408 response to heat; GO:0009410 response to xenobiotic stimulus; GO:0009555 pollen development; GO:0009749 response to glucose; GO:0009898 cytoplasmic side of plasma membrane; GO:0010008 endosome membrane; GO:0010043 response to zinc ion; GO:0010467 gene expression; GO:0010628 positive regulation of gene expression; GO:0010666 positive regulation of cardiac muscle cell apoptotic process; GO:0010719 negative regulation of epithelial to mesenchymal transition; GO:0010888 negative regulation of lipid storage; GO:0010975 regulation of neuron projection development; GO:0010977 negative regulation of neuron projection development; GO:0010997 anaphase-promoting complex binding; GO:0014069 postsynaptic density; GO:0014823 response to activity; GO:0016239 positive regulation of macroautophagy; GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; GO:0016324 apical plasma membrane; GO:0016477 cell migration; GO:0016525 negative regulation of angiogenesis; GO:0016791 phosphatase activity; GO:0019899 enzyme binding; GO:0019901 protein kinase binding; GO:0021542 dentate gyrus development; GO:0021955 central nervous system neuron axonogenesis; GO:0022604 regulation of cell morphogenesis; GO:0030010 establishment of cell polarity; GO:0030036 actin cytoskeleton organization; GO:0030041 actin filament polymerization; GO:0030097 hemopoiesis; GO:0030165 PDZ domain binding; GO:0030308 negative regulation of cell growth; GO:0030336 negative regulation of cell migration; GO:0030351 inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity; GO:0030424 axon; GO:0030425 dendrite; GO:0030435 sporulation resulting in formation of a cellular spore; GO:0030534 adult behavior; GO:0030587 sorocarp development; GO:0030707 follicle cell of egg chamber development; GO:0030835 negative regulation of actin filament depolymerization; GO:0031038 myosin II filament organization; GO:0031104 dendrite regeneration; GO:0031152 aggregation involved in sorocarp development; GO:0031174 lifelong otolith mineralization; GO:0031175 neuron projection development; GO:0031254 cell trailing edge; GO:0031257 cell trailing edge membrane; GO:0031269 pseudopodium assembly; GO:0031271 lateral pseudopodium assembly; GO:0031272 regulation of pseudopodium assembly; GO:0031273 negative regulation of pseudopodium assembly; GO:0031642 negative regulation of myelination; GO:0031647 regulation of protein stability; GO:0032060 bleb assembly; GO:0032154 cleavage furrow; GO:0032228 regulation of synaptic transmission, GABAergic; GO:0032286 central nervous system myelin maintenance; GO:0032355 response to estradiol; GO:0032535 regulation of cellular component size; GO:0032755 positive regulation of interleukin-6 production; GO:0032760 positive regulation of tumor necrosis factor production; GO:0032869 cellular response to insulin stimulus; GO:0033032 regulation of myeloid cell apoptotic process; GO:0033137 negative regulation of peptidyl-serine phosphorylation; GO:0033198 response to ATP; GO:0033555 multicellular organismal response to stress; GO:0034461 uropod retraction; GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; GO:0035011 melanotic encapsulation of foreign target; GO:0035069 larval midgut histolysis; GO:0035176 social behavior; GO:0035204 negative regulation of lamellocyte differentiation; GO:0035206 regulation of hemocyte proliferation; GO:0035212 cell competition in a multicellular organism; GO:0035255 ionotropic glutamate receptor binding; GO:0035749 myelin sheath adaxonal region; GO:0036051 protein localization to trailing edge; GO:0036052 protein localization to uropod; GO:0036294 cellular response to decreased oxygen levels; GO:0040014 regulation of multicellular organism growth; GO:0040015 negative regulation of multicellular organism growth; GO:0040024 dauer larval development; GO:0042052 rhabdomere development; GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway; GO:0042577 lipid phosphatase activity; GO:0042594 response to starvation; GO:0042690 negative regulation of crystal cell differentiation; GO:0042711 maternal behavior; GO:0042802 identical protein binding; GO:0042995 cell projection; GO:0043005 neuron projection; GO:0043025 neuronal cell body; GO:0043065 positive regulation of apoptotic process; GO:0043066 negative regulation of apoptotic process; GO:0043197 dendritic spine; GO:0043204 perikaryon; GO:0043220 Schmidt-Lanterman incisure; GO:0043327 chemotaxis to cAMP; GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction; GO:0043542 endothelial cell migration; GO:0044320 cellular response to leptin stimulus; GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation; GO:0045211 postsynaptic membrane; GO:0045471 response to ethanol; GO:0045475 locomotor rhythm; GO:0045571 negative regulation of imaginal disc growth; GO:0045614 negative regulation of plasmatocyte differentiation; GO:0045666 positive regulation of neuron differentiation; GO:0045668 negative regulation of osteoblast differentiation; GO:0045786 negative regulation of cell cycle; GO:0045792 negative regulation of cell size; GO:0045944 positive regulation of transcription by RNA polymerase II; GO:0046580 negative regulation of Ras protein signal transduction; GO:0046621 negative regulation of organ growth; GO:0046627 negative regulation of insulin receptor signaling pathway; GO:0046628 positive regulation of insulin receptor signaling pathway; GO:0046685 response to arsenic-containing substance; GO:0046856 phosphatidylinositol dephosphorylation; GO:0048008 platelet-derived growth factor receptor signaling pathway; GO:0048167 regulation of synaptic plasticity; GO:0048542 lymph gland development; GO:0048679 regulation of axon regeneration; GO:0048681 negative regulation of axon regeneration; GO:0048738 cardiac muscle tissue development; GO:0048853 forebrain morphogenesis; GO:0048854 brain morphogenesis; GO:0048870 cell motility; GO:0050680 negative regulation of epithelial cell proliferation; GO:0050765 negative regulation of phagocytosis; GO:0050771 negative regulation of axonogenesis; GO:0050773 regulation of dendrite development; GO:0050821 protein stabilization; GO:0050919 negative chemotaxis; GO:0050920 regulation of chemotaxis; GO:0050927 positive regulation of positive chemotaxis; GO:0051285 cell cortex of cell tip; GO:0051490 negative regulation of filopodium assembly; GO:0051491 positive regulation of filopodium assembly; GO:0051548 negative regulation of keratinocyte migration; GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; GO:0051726 regulation of cell cycle; GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; GO:0051895 negative regulation of focal adhesion assembly; GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; GO:0052866 phosphatidylinositol phosphate phosphatase activity; GO:0055088 lipid homeostasis; GO:0060024 rhythmic synaptic transmission; GO:0060027 convergent extension involved in gastrulation; GO:0060044 negative regulation of cardiac muscle cell proliferation; GO:0060074 synapse maturation; GO:0060134 prepulse inhibition; GO:0060179 male mating behavior; GO:0060291 long-term synaptic potentiation; GO:0060292 long-term synaptic depression; GO:0060341 regulation of cellular localization; GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway; GO:0060736 prostate gland growth; GO:0060766 negative regulation of androgen receptor signaling pathway; GO:0060997 dendritic spine morphogenesis; GO:0061002 negative regulation of dendritic spine morphogenesis; GO:0061066 positive regulation of dauer larval development; GO:0061515 myeloid cell development; GO:0062049 protein phosphatase inhibitor complex; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:0071257 cellular response to electrical stimulus; GO:0071361 cellular response to ethanol; GO:0071456 cellular response to hypoxia; GO:0071545 inositol phosphate catabolic process; GO:0071711 basement membrane organization; GO:0072709 cellular response to sorbitol; GO:0080025 phosphatidylinositol-3,5-bisphosphate binding; GO:0090071 negative regulation of ribosome biogenesis; GO:0090175 regulation of establishment of planar polarity; GO:0090394 negative regulation of excitatory postsynaptic potential; GO:0097105 presynaptic membrane assembly; GO:0097107 postsynaptic density assembly; GO:0097225 sperm midpiece; GO:0097228 sperm principal piece; GO:0099092 postsynaptic density, intracellular component; GO:0099524 postsynaptic cytosol; GO:0140678 molecular function inhibitor activity; GO:0140986 G protein-coupled chemorepellent receptor signaling pathway; GO:1900425 negative regulation of defense response to bacterium; GO:1901017 negative regulation of potassium ion transmembrane transporter activity; GO:1901888 regulation of cell junction assembly; GO:1902074 response to salt; GO:1902533 positive regulation of intracellular signal transduction; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:1903665 negative regulation of asexual reproduction; GO:1903690 negative regulation of wound healing, spreading of epidermal cells; GO:1903860 negative regulation of dendrite extension; GO:1904262 negative regulation of TORC1 signaling; GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation; GO:1905235 response to quercetin; GO:1990090 cellular response to nerve growth factor stimulus; GO:1990314 cellular response to insulin-like growth factor stimulus; GO:1990381 ubiquitin-specific protease binding; GO:1990753 equatorial cell cortex; GO:1990757 ubiquitin ligase activator activity; GO:1990782 protein tyrosine kinase binding; GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:2000272 negative regulation of signaling receptor activity; GO:2000463 positive regulation of excitatory postsynaptic potential; GO:2000773 negative regulation of cellular senescence; GO:2000808 negative regulation of synaptic vesicle clustering; GO:2001235 positive regulation of apoptotic signaling pathway

KEGG

EC: ec:3.1.3.16, ec:3.1.3.48, ec:3.1.3.67 | KO: K01110 | Pathway: 00562, 01100, 04070 | BRITE: 00001, 01000, 01009